PBT:  Bioaccumulative
u Bioaccumulate ->  build up in a food chain
u Greater concentrations  at higher trophic levels
– Concentrations can be very low in air and water but
much greater in fish or mammals; up to 1,000,000
times higher
– Polar bears, tuna, children
– Accumulate in fat (PCBs) or muscle (methylmercury)
– Foods tend to be most significant sources for adults
u Children may receive greatest exposures from
their mothers
– In utero and breastfeeding